Figure 5.

The kidney phenotype caused by EHHADH deficiency in mice is androgen dependent. (A) Representative images of KIM-1 IF in sham-operated and orchiectomized WT and Ehhadh KO male mice. (B) Quantification of KIM-1⁺ cells per mm² in sham-operated and orchiectomized WT and Ehhadh KO male mice. Statistical significance was tested using two-way ANOVA with “Genotype” and “Orchiectomy” as the two factors (B). *P<0.05. Scale bars = 100 µm.