Table 2.

Abundance of taxa associated (FDR <0.10) with risk of lung cancer in two prospective cohorts of never-smokers^*

	Medium vs low abundance				High vs low abundance
		95% CI				95% CI
Taxa†	OR	Lower	Upper	P value	OR	Lower	Upper	P value	Ptrend	FDR
Spirochaetes (p), Spirochaetia (c)	0.61	0.32	1.18	0.14	0.42	0.21	0.85	0.02	0.01	0.08
Bacteroidetes (p), Bacteroidetes (c)	0.66	0.35	1.25	0.21	0.31	0.15	0.64	0.002	0.002	0.03
Bacteroidetes (p), Bacteroidetes (c), Bacteroidetes (o)	0.66	0.35	1.25	0.21	0.31	0.15	0.64	0.002	0.002	0.02
Bacteroidetes (p), Bacteroidetes (c), Bacteroidetes (o), Bacteroidetes (f)	0.66	0.35	1.25	0.21	0.31	0.15	0.64	0.002	0.002	0.06
Firmicutes (p), Bacilli (c)	1.49	0.73	3.08	0.28	2.40	1.18	4.87	0.02	0.01	0.08
Firmicutes (p), Bacilli (c), Lactobacillales (o)	2.15	1.03	4.47	0.04	3.26	1.58	6.70	0.001	0.002	0.02

^*Adjusted for sex, age, sample collection time, menopause status (for women), education and antibiotic use.

^†Indicated by phylogenetic tree attributes (p=phylum; c=class; o=order; f=family).

FDR, false discovery rate.