Table 3.
The univariate analysis of DUSP11 and other clinicopathological factors.
| Clinicopathologicparameters | iCCA | pCCA | dCCA | ||||
|---|---|---|---|---|---|---|---|
| 5-year OS | P* | 5-year OS | P* | 5-year OS | P* | ||
| Age (years) |
<60 | 36.1 | 0.435 | 40.6 | 0.142 | 43.8 | 0.600 |
| ≥60 | 28.3 | 36.4 | 54.7 | ||||
| Sex | Male | 31.5 | 0.288 | 37.8 | 0.789 | 37.8 | 0.789 |
| Female | 35.3 | 35.1 | 35.1 | ||||
| Tumor size#
(cm) |
<3/5 cm | 44.7 | 0.007 | 41.9 | 0.329 | 41.9 | 0.389 |
| ≥3/5 cm | 22.8 | 41.1 | 32.9 | ||||
| Differentiation | Well | 35.6 | 49.0 | 64.3 | |||
| Moderately | 31.9 | 0.586 | 10.1 | 0 | 48.1 | 0.851 | |
| Poorly | 33.3 | 0 | 41.5 | ||||
| T stage | T1 + 2 | 39.9 | 0.219 | 52.9 | 0.004 | 34.8 | 0.647 |
| T3 + 4 | 16.7 | 27.3 | 43.8 | ||||
| N stage | N0 | 42.4 | 0.010 | 46.3 | 0.006 | 32.3 | 0.110 |
| N1 | 12.4 | 0 | 61.1 | ||||
| M stage | M0 | 35.7 | 0.010 | 39.1 | 0.012 | ||
| M1 | 0 | 0 | |||||
| TNM stage | I | 47.1 | 75.0 | 34.4 | |||
| II | 58.3 | 0.049 | 26.8 | 0.049 | 46.6 | 0.292 | |
| III | 22.5 | 30.8 | 0 | ||||
| IV | 13.0 | 28 | |||||
| DUSP11 | Low | 52.6 | 0.002 | 47.5 | 0.354 | 50.0 | 0.459 |
| High | 9.4 | 25.2 | 45.9 | ||||
*represents analysis with log-rank test; #represents 5 cm for iCCA and 3 cm for pCCA/dCCA.