. 2021 Apr 19;138(9):773–784. doi: 10.1182/blood.2020010510

Table 1.

Details of BCL11B-a AL cases

Case	Code	Sex/age, y	FAB/WHO diagnosis	Immunophenotype	Karyotype
t(2;14)(q22;q32)
1	UPN#455	M/72	AML	NA	46,XY,t(2;14)(q22;q32)[4]/46,XY[9]
2	UPN#456	M/52	T/myeloid MPAL	CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD13⁺, TdT⁺, cCD3⁺, CD56⁺, MPO⁺, cCD79a⁺, CD7⁻, CD3⁻, CD5⁻, CD33⁻, CD14⁻, CD15⁻, CD22⁻, CD20⁻	46,XY,t(2;14)(q22;q32)[19]/47,idem,+4[3]
3	UPN#457	M/37	AML M0	CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD13⁺, TdT⁺, CD7⁺, CD15⁺, MPO^+/−, CD33^+/−, CD14⁻, CD11c⁻, CD3⁻, CD4⁻, CD8⁻, CD5⁻, CD10⁻, CD19⁻	46,XY,t(2;14)(q22;q32)[15]
4	UPN#141	F/76	AML M0	CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD13⁺, CD7⁺, MPO⁺, CD11b⁺, CD38⁺, CD33⁻, CD14⁻, CD15⁻, cCD3⁻, CD3⁻, CD4⁻, CD56⁻, CD10⁻, cCD79a⁻, CD19⁻	46,XX,t(2;14)(q22;q32),del(5) (q13q31)[15]
5	UPN#458	F/68	AML M1	CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD13⁺, CD7⁺, MPO^+/−, CD33⁺, CD14⁻, TdT⁻, CD3⁻, CD4⁻, CD8⁻, CD1a⁻, CD10⁻, CD19⁻, CD22⁻	46,XX,t(2;14)(q22;q32)[12]/ 46,idem,add(12)(q24)[5]/ 46,XX[3]
6	UPN#151	M/18	AML M1	CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD13⁺, CD15⁺, CD56⁺, MPO⁻, CD33⁻, CD14⁻, CD7⁻, cCD3⁻, CD3⁻, CD4⁻, CD5⁻, CD19⁻, cCD79a⁻	46,XY,t(2;14)(q22;q32),del(16) (q21)[15]
7	UPN#459	M/64	ETP-ALL	CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD13⁺, CD11b⁺, CD56⁺, TdT⁺, CD7⁺, CD38⁺, cCD3⁺, MPO⁻, CD33⁻, CD4⁻, CD5⁻, CD1a⁻, CD10⁻, CD19⁻, CD20⁻, cCD79a⁻	46,XY[24].ish t(2;14)(q22;q32) (WI2-2194I13+; WI2-2001J18+)[5]
t(6;14)(q25;q32)
8	UPN#143	M/17	AML-M1	CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD13⁺, TdT⁺, CD33⁺, MPO⁺, CD56⁺, CD15⁺, CD14⁻, CD7⁻, cCD3⁻, CD3⁻, CD4⁻, CD5⁻, CD10⁻, CD19⁻, CD20⁻, cCD79a⁻	46,XY,t(6;14)(q25;q32)[15]
9	UPN#145	M/59	T/myeloid MPAL	CD2⁺, CD117⁺, CD34⁺, CD13⁺, CD7⁺, TdT⁺, cCD3⁺, CD3⁻, CD8⁻, CD4⁻, CD5⁻, CD1a⁻, CD10⁻, cCD79a⁻, CD2⁺, CD13⁺, CD33⁺, CD11b⁺, MPO⁺, CD14⁺, CD34⁻, CD117⁻, CD10⁻, cCD79a⁻	46,XY,t(6;14)(q25;q32),del(11) (p13p15)[15]
10	UPN#460	M/48	ETP-ALL	CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD13⁺, CD7⁺, TdT⁺, CD33⁺, CD38⁺, CD45⁺, CD99⁺, CD133⁺, cCD3⁺, CD3⁻, CD4⁻, CD5⁻, CD8⁻, CD52⁻, CD56⁻, CD65⁻, CD79a⁻, MPO⁻, TCR A/B⁻, TCR G/D⁻, CD10⁻, CD19⁻, cCD79a⁻	46,XY,add(19)(q13)[10]/ 46,XY[5].ish ins(6;14) (q25;q32q32) (WI2-2194I13+; WI2-2934J16+)[6]
11	UPN#260	M/4	ETP-ALL	CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD33⁺, CD7⁺, TdT⁺, CD38⁺, CD45⁺, cCD3⁺, CD11b⁺, MPO^+/−, CD99⁺, CD3⁻, CD4⁻, CD5⁻, CD8⁻, CD1a⁻, CD56⁻, CD13⁻, CD14⁻, CD14⁻, CD65⁻, CD10⁻, CD19⁻	46,XY[10].ish t(6;14)(q25;q32) (WI2-2194I13+; WI2-2001J18+)[5]
12	UPN#462	F/78	ETP-ALL	CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD13⁺, CD7⁺, CD38⁺, cCD3⁺, TdT⁻, CD4⁻, CD8⁻, CD3⁻, CD5⁻, CD56⁻, CD79a⁻, CD15⁻, CD33⁻, MPO⁻, CD61⁻, CD10⁻, CD19⁻, CD20⁻, CD22⁻, cCD79a⁻	47,XX,+4[8]/46,XX[8].nuc ish(WI2-2001J18X2),(WI2-2194I13X2),(WI2-2001J18 sep WI2-2194I13X1) [70/100]
13	UPN#463	M/18	T-ALL unspecified	NA	47,XY,+4[15]/46,XY[15].ish t(6; 14)(q25;q32)(WI2-2194I13+; WI2-2001J18+)[3]
14	UPN#464	M/29	T-ALL unspecified	NA	nuc ish(WI2-2001J18X2),(WI2- 2194I13X2),(WI2-2001J18 sep WI2-2194I13X1)[70/106]
15	UPN#465	M/12	ETP-ALL	NA	46,XY,t(6;14)(q25;q32),del(12) (p11p13)[9]/46,XY[6]
16	UPN#466	M/44	ETP-ALL	CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD13⁺, CD7⁺, CD38⁺, TdT⁺, CD33⁻, sCD3⁻, CD4⁻, CD8⁻, CD5⁻, CD56⁻, CD10⁻, CD19⁻	46,XY,t(6;14)(q25;q32) [9]/46,XY[3]
t(7;14)(q22;q32)
17	UPN#149	M/51	ETP-ALL	CD2⁺, CD117⁺, CD34⁺, HLA-DR^+/−, cCD3⁺, TdT⁺, CD7^+/−, CD15^+/−, sCD3⁻, CD5⁻, CD4⁻, CD8⁻, MPO⁻, CD13⁻, CD33⁻, CD10⁻, cCD79a⁻	46,XY,t(7;14)(q21;q32) [16]/46,XY[5]
18	UPN#147	M/50	T/myeloid MPAL	CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD7⁺, CD38⁺, CD15⁺, CD3⁺, CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD33dim, CD13dim, CD7⁺, CD38⁺, CD15⁺, MPO⁺, CD36⁺, CD123⁺, CD10⁻, CD19⁻, CD22⁻, cCD79a⁻	46,XY,t(7;14)(q21;q32) [9]/46,XY[1]
t(8;14)(q24;q32)
19	UPN#461	M/65	AML M0	CD2⁺, CD117⁺, CD34⁺, HLA-DR^+/−, CD13⁺, CD7⁺, cCD3⁻, CD3⁻, CD4⁻, CD1a⁻, CD5⁻, CD8⁻, MPO⁻, TdT⁻, CD10⁻, CD19⁻	46,XY,t(2;5)(p21;q13)[10]/46,XX[9].nuc ish(WI2-2194I13X2),(WI2-2934J16X2),(WI2-2194I13 sep WI2-2934J16)[100/120]
20	UPN#467	M/51	AML M0	CD2⁺, CD117⁺, CD34⁺, HLA-DR⁺, CD13⁺, CD7⁺, MPO⁻, CD33⁻, cCD3⁻, CD3⁻, CD8⁻, CD5⁻, CD56⁻, CD19⁻, cCD79a⁻	46,XY[10].nuc ish(WI2-2194I13X2),(WI2-2934J16X2),(WI2-2194I13 sep WI2-2934J16)[91/100]

Positive antigens common to all cases with available immunophenotype and the 14q32/BCL11B translocation are indicated in bold. NA, not available.