Source	Search strategy	Hits retrieved
CENTRAL via CRSO	#1 MESH DESCRIPTOR Arteriosclerosis 946 #2 MESH DESCRIPTOR Arteriolosclerosis 0 #3 MESH DESCRIPTOR Arteriosclerosis Obliterans 78 #4 MESH DESCRIPTOR Atherosclerosis 1061 #5 MESH DESCRIPTOR Arterial Occlusive Diseases 819 #6 MESH DESCRIPTOR Intermittent Claudication 825 #7 MESH DESCRIPTOR Ischemia 1542 #8 MESH DESCRIPTOR Peripheral Vascular Diseases EXPLODE ALL TREES 2783 #9 MESH DESCRIPTOR Vascular Diseases 645 #10 MESH DESCRIPTOR Leg EXPLODE ALL TREES 2801 #11 MESH DESCRIPTOR Femoral Artery EXPLODE ALL TREES 904 #12 MESH DESCRIPTOR Popliteal Artery EXPLODE ALL TREES 304 #13 MESH DESCRIPTOR Iliac Artery EXPLODE ALL TREES 159 #14 MESH DESCRIPTOR Tibial Arteries EXPLODE ALL TREES 38 #15 (atherosclero* or arteriosclero* or PVD or PAOD or PAD):TI,AB,KY 12285 #16 ((arter*) near (*occlus* or steno* or obstuct* or lesio* or block* or obliter*) ):TI,AB,KY 6367 #17 ((vascular) near (*occlus* or steno* or obstuct* or lesio* or block* or obliter*) ):TI,AB,KY 842 #18 ((veno*) near (*occlus* or steno* or obstuct* or lesio* or block* or obliter*) ):TI,AB,KY 1151 #19 ((vein*) near (*occlus* or steno* or obstuct* or lesio* or block* or obliter*) ):TI,AB,KY 1346 #20 ((peripher*) near (*occlus* or steno* or obstuct* or lesio* or block* or obliter*) ):TI,AB,KY 2358 #21 (peripheral near/3 dis* ):TI,AB,KY 0 #22 arteriopathic:TI,AB,KY 7 #23 (claudic* or hinken*):TI,AB,KY 1880 #24 (isch* or CLI):TI,AB,KY 32430 #25 dysvascular*:TI,AB,KY 23 #26 (leg near4 (obstruct* or occlus* or steno* or block* or obliter*) ):TI,AB,KY 155 #27 (limb near4 (obstruct* or occlus* or steno* or block* or obliter*) ):TI,AB,KY 239 #28 ((lower near3 extrem*) near4 (obstruct* or occlus* or steno* or block* or obliter*) ):TI,AB,KY 103 #29 ((aort* or iliac or femoral or popliteal or femoro* or fempop* or crural) near3 (obstruct* or occlus*) ):TI,AB,KY 454 #30 #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 or #14 or #15 or #16 or #17 or #18 or #19 or #20 or #21 or #22 or #23 or #24 or #25 or #26 or #27 or #28 or #29 56041 #31 MESH DESCRIPTOR Atherectomy 24 #32 atherect*:TI,AB,KY 333 #33 (SilverHawk or "Silver Hawk" ):TI,AB,KY 12 #34 Jetstream:TI,AB,KY 2 #35 (plaque near3 excis*):TI,AB,KY 12 #36 (atheroablation or rotational or orbital):TI,AB,KY 1514 #37 (angle near3 blade*):TI,AB,KY 10 #38 (cut near3 blade*):TI,AB,KY 1 #39 (blade near3 cathet*):TI,AB,KY 1 #40 EV3:TI,AB,KY 10 #41 #31 or #32 or #33 or #34 or #35 or #36 or #37 or #38 or #39 or #40 1735 #42 #30 AND #41 201 #43 01/11/2013 TO 20/08/2018:CD 584598 #44 #42 AND #43 110	20 August 2018: 110 12 August 2019: 57
Clinicaltrials.gov	peripheral arterial disease OR artery OR vascular OR Arteriosclerosis OR Ischemia | Atherectomy OR atheroablation OR rotational OR orbital OR EV3 | Start date on or after 01/01/2013 | Last update posted on or before 08/08/2019	20 August 2018: 76 12 August 2019: 36
ICTRP Search Portal	peripheral arterial disease OR artery OR vascular OR Arteriosclerosis OR Ischemia | Atherectomy OR atheroablation OR rotational OR orbital OR EV3 | Start date on or after 01/01/2013 | Last update posted on or before 08/08/2019	20 August 2018: 41 12 August 2019: 14
Ovid MEDLINE® Epub Ahead of Print, In‐Process & Other Non‐Indexed Citations, Ovid MEDLINE® Daily and Ovid MEDLINE®	1 ARTERIOSCLEROSIS/ 56458 2 ARTERIOLOSCLEROSIS/ 150 3 Arteriosclerosis Obliterans/ 3977 4 ATHEROSCLEROSIS/ 31372 5 Arterial Occlusive Diseases/ 26551 6 Intermittent Claudication/ 7623 7 ISCHEMIA/ 47700 8 exp Peripheral Vascular Diseases/ 50278 9 Vascular Diseases/ 35016 10 exp LEG/bs [Blood Supply] 25052 11 exp Femoral Artery/ 27179 12 exp Popliteal Artery/ 9025 13 exp Iliac Artery/ 13402 14 exp Tibial Arteries/ 1501 15 (atherosclero* or arteriosclero* or PVD or PAOD or PAD).ti,ab. 172197 16 (arter* adj (occlus* or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 63236 17 (vascular adj (occlus* or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 15842 18 (vein* adj (occlus* or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 7223 19 (veno* adj (occlus* or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 7897 20 (peripher* adj (occlus* or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 1931 21 (peripheral adj3 dis*).ti,ab. 38014 22 arteriopathic.ti,ab. 162 23 (claudic* or hinken*).ti,ab. 9857 24 (isch* or CLI).ti,ab. 347912 25 (leg adj4 (obstruct* or occlus* or steno* or block* or obliter*)).ti,ab. 591 26 (limb adj4 (obstruct* or occlus* or steno* or block* or obliter*)).ti,ab. 1841 27 (lower adj3 extrem* adj4 (obstruct* or occlus* or steno* or block* or obliter*)).ti,ab. 1541 28 ((aort* or iliac or femoral or popliteal or femoro* or fempop* or crural) adj3 (obstruct* or occlus*)).ti,ab. 8681 29 dysvascular*.ti,ab. 219 30 or/1‐29 732181 31 ATHERECTOMY/ 667 32 atherect*.ti,ab. 2759 33 (SilverHawk or "Silver Hawk").ti,ab. 66 34 Jetstream.ti,ab. 31 35 (plaque adj3 excis*).ti,ab. 209 36 (atheroablation or rotational or orbital).ti,ab. 90480 37 (angle adj3 blade*).ti,ab. 112 38 (cut adj3 blade*).ti,ab. 80 39 (blade adj3 cathet*).ti,ab. 10 40 EV3.ti,ab. 238 41 or/31‐40 93104 42 30 and 41 3188 43 randomized controlled trial.pt. 467015 44 controlled clinical trial.pt. 92591 45 randomized.ab. 419437 46 placebo.ab. 191087 47 drug therapy.fs. 2041052 48 randomly.ab. 295632 49 trial.ab. 436703 50 groups.ab. 1824460 51 or/43‐50 4263409 52 exp animals/ not humans.sh. 4488176 53 51 not 52 3685450 54 42 and 53 555 55 (2017* or 2018*).ed. 1598344 56 54 and 55 59 57 from 56 keep 1‐59 59	20 August 2018: 59 12 August 2019: 59
EMBASE	1 arteriosclerosis/ 23302 2 arteriolosclerosis/ 539 3 peripheral occlusive artery disease/ 29354 4 atherosclerosis/ 130224 5 peripheral occlusive artery disease/ 29354 6 intermittent claudication/ 8546 7 ischemia/ 70896 8 exp peripheral vascular disease/ 1521794 9 vascular disease/ 50928 10 exp femoral artery/ 28864 11 exp popliteal artery/ 7120 12 exp iliac artery/ 15142 13 exp tibial artery/ 2504 14 (atherosclero* or arteriosclero* or PVD or PAOD or PAD).ti,ab. 221645 15 (arter* adj (*occlus*/ or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 81145 16 (vascular adj (*occlus*/ or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 19845 17 (vein* adj (*occlus*/ or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 9432 18 (veno* adj (*occlus*/ or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 10130 19 (peripher* adj (*occlus*/ or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 2816 20 (peripheral adj3 dis*).ti,ab. 51397 21 arteriopathic.ti,ab. 179 22 (claudic* or hinken*).ti,ab. 12594 23 (isch* or CLI).ti,ab. 478952 24 dysvascular*.ti,ab. 229 25 (leg adj4 (obstruct* or occlus* or steno* or block* or obliter*)).ti,ab. 731 26 (limb adj4 (obstruct* or occlus* or steno* or block* or obliter*)).ti,ab. 2595 27 (lower dj3 extrem* adj4 (obstruct* or occlus* or steno* or block* or obliter*)).ti,ab. 0 28 ((aort* or iliac or femoral or popliteal or femoro* or fempop* or crural) adj3 (obstruct* or occlus*)).ti,ab. 10343 29 or/1‐28 1820971 30 atherectomy/ 3475 31 atherect*.ti,ab. 3818 32 (SilverHawk or "Silver Hawk").ti,ab. 118 33 Jetstream.ti,ab. 65 34 (plaque adj3 excis*:).ti,ab. 355 35 (atheroablation or rotational or orbital).ti,ab. 82052 36 (angle adj3 blade*).ti,ab. 158 37 (cut adj3 blade*:).ti,ab. 97 38 (cut adj3 blade*).ti,ab. 97 39 (blade adj3 cathet*).ti,ab. 12 40 EV3.ti,ab. 443 41 or/30‐40 86520 42 29 and 41 9677 43 randomized controlled trial/ 485173 44 controlled clinical trial/ 453439 45 random$.ti,ab. 1255139 46 randomization/ 78361 47 intermethod comparison/ 224177 48 placebo.ti,ab. 263135 49 (compare or compared or comparison).ti. 439907 50 ((evaluated or evaluate or evaluating or assessed or assess) and (compare or compared or comparing or comparison)).ab. 1683247 51 (open adj label).ti,ab. 61750 52 ((double or single or doubly or singly) adj (blind or blinded or blindly)).ti,ab. 201070 53 double blind procedure/ 144969 54 parallel group$1.ti,ab. 20900 55 (crossover or cross over).ti,ab. 89795 56 ((assign$ or match or matched or allocation) adj5 (alternate or group$1 or intervention$1 or patient$1 or subject$1 or participant$1)).ti,ab. 271905 57 (assigned or allocated).ti,ab. 320231 58 (controlled adj7 (study or design or trial)).ti,ab. 281124 59 (volunteer or volunteers).ti,ab. 217649 60 trial.ti. 234748 61 or/43‐60 3866425 62 42 and 61 1797 63 (2017* or 2018*).em. 2796615 64 62 and 63 278 65 from 64 keep 1‐278 278	20 August 2018: 278 12 August 2019: 361
CINAHL	S53 S51 AND S52 9 S52 EM 2016 OR EM 2017 334,593 S51 S40 AND S50 72 S50 S41 OR S42 OR S43 OR S44 OR S45 OR S46 OR S47 OR S48 OR S49 267,359 S49 MH "Single‐Blind Studies" or MH "Double‐Blind Studies" or MH "Triple‐Blind Studies" 32,871 S48 MH "Factorial Design" 922 S47 MH "Placebos" 8,375 S46 MH "Clinical Trials" 93,030 S45 TX "multi‐centre study" OR "multi‐center study" OR "multicentre study" OR "multicenter study" OR "multi‐site study" 4,542 S44 TX crossover OR "cross‐over" 14,660 S43 AB placebo* 28,580 S42 TX trial* 252,485 S41 TX "latin square" 143 S40 S28 AND S39 293 S39 S29 OR S30 OR S31 OR S32 OR S33 OR S34 OR S35 OR S36 OR S37 OR S38 4,240 S38 TX EV3 15 S37 TX blade N3 cathet* 0 S36 TX cut N3 blade* 0 S35 TX angle N3 blade* 0 S34 TX atheroablation or rotational or orbital 4,010 S33 TX plaque N3 excis* 0 S32 TX Jetstream 3 S31 TX SilverHawk or "Silver Hawk" 10 S30 TX atherect* 317 S29 (MH "Atherectomy") 82 S28 S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 OR S25 OR S26 OR S27 75,396 S27 TX dysvascular* 172 S26 TX aort* or iliac or femoral or popliteal or femoro* or fempop* or crural) N3 (obstruct* or occlus*) 583 S25 TX lower N3 extrem* N4 (obstruct* or occlus* or steno* or block* or obliter*) 82 S24 TX limb N4 (obstruct* or occlus* or steno* or block* or obliter*) 198 S23 TX leg N4 (obstruct* or occlus* or steno* or block* or obliter*) 92 S22 TX isch* or CLI 39,707 S21 TX claudic* or hinken* 1,389 S20 TX arteriopathic 10 S19 TX peripheral N3 dis* 9,270 S18 TX peripher* N (occlus* or steno* or obstuct* or lesio* or block* or obliter*) 10 S17 TX veno* N (occlus* or steno* or obstuct* or lesio* or block* or obliter*) 11 S16 TX vein* N (occlus* or steno* or obstuct* or lesio* or block* or obliter*) 7 S15 TX vascular N (occlus* or steno* or obstuct* or lesio* or block* or obliter*) 13 S14 TX arter* N (occlus* or steno* or obstuct* or lesio* or block* or obliter* 167 S13 TX atherosclero* or arteriosclero* or PVD or PAOD or PAD 26,503 S12 (MH "Tibial Arteries") 145 S11 (MH "Iliac Artery") 453 S10 (MH "Popliteal Artery") 359 S9 (MH "Femoral Artery") 1,188 S8 (MH "Leg/BS") 450 S7 (MH "Vascular Diseases") 2,381 S6 (MH "Peripheral Vascular Diseases") 0 S5 (MH "Ischemia") 3,387 S4 (MH "Intermittent Claudication") 841 S3 (MH "Arterial Occlusive Diseases") 1,602 S2 (MH "Atherosclerosis") 3,372 S1 (MH "Arteriosclerosis") 4,820	20 August 2018: 9 12 August 2019: 31
AMED	1 ARTERIOSCLEROSIS/ 78 2 ATHEROSCLEROSIS/ 223 3 Intermittent Claudication/ 75 4 ISCHEMIA/ 266 5 (atherosclero* or arteriosclero* or PVD or PAOD or PAD).ti,ab. 810 6 (arter* adj (occlus* or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 179 7 (vascular adj (occlus* or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 44 8 (vein* adj (occlus* or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 4 9 (veno* adj (occlus* or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 29 10 (peripher* adj (occlus* or steno* or obstuct* or lesio* or block* or obliter*)).ti,ab. 11 11 (peripheral adj3 dis*).ti,ab. 439 12 arteriopathic.ti,ab. 1 13 (claudic* or hinken*).ti,ab. 150 14 (isch* or CLI).ti,ab. 1687 15 (leg adj4 (obstruct* or occlus* or steno* or block* or obliter*)).ti,ab. 19 16 (limb adj4 (obstruct* or occlus* or steno* or block* or obliter*)).ti,ab. 22 17 (lower adj3 extrem* adj4 (obstruct* or occlus* or steno* or block* or obliter*)).ti,ab. 12 18 ((aort* or iliac or femoral or popliteal or femoro* or fempop* or crural) adj3 (obstruct* or occlus*)).ti,ab. 11 19 dysvascular*.ti,ab. 58 20 or/1‐19 3220 21 (atheroablation or rotational or orbital).ti,ab. 573 22 (angle adj3 blade*).ti,ab. 4 23 or/21‐22 577 24 20 and 23 4 25 exp CLINICAL TRIALS/ 3788 26 RANDOM ALLOCATION/ 314 27 DOUBLE BLIND METHOD/ 667 28 Clinical trial.pt. 1212 29 (clinic* adj trial*).tw. 5438 30 ((singl* or doubl* or trebl* or tripl*) adj (blind* or mask*)).tw. 2866 31 PLACEBOS/ 591 32 placebo*.tw. 3132 33 random*.tw. 17749 34 PROSPECTIVE STUDIES/ 1119 35 or/25‐34 22789 36 24 and 35 0	20 August 2018: 0 12 August 2019: 0