Table 1.
Studies investigating the prevalence and mortality of neurologic complications in adult patients on ECMO.
| References | Number of enrolled patients | Prevalence% (mortality%) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| ECMO | VA ECMO | VV ECMO | ICH | AIS | Seizures | HIBI | BD | ||
| Sutter et al. (2) | N/A | 13.0 (83.0) | 15.0 | 10.0 | 5.0 (96.0) | 7.0 (83.0) | 2.0 (40.0) | N/A | N/A |
| Shoskes et al. (5) | 16,063 (VA 8211, VV 7842) | 16.0 (47.0) | 19.0 (52.0) | 10.0 (36.0) | 7.0 | 7.0 | 1.0 | 8.0 | N/A |
| Chapman et al. (6) | 412 (VA 244, VV 131, Other type 37) | 13.3 (65.0) | 18.0 | 4.5 | 3.4 | 7.0 | N/A | 3.6 | N/A |
| Lorusso et al. (7) | 4,522 (all VA) | N/A | 15.1 (90.0) | N/A | 1.8 | 3.6 | 1.8 | N/A | 7.9 |
| Lorusso et al. (8) | 4,988 (all VV) | N/A | N/A | 7.1 (75.8) | 3.6 (79.6) | 1.7 (68.2) | 1.2 (50.0) | N/A | 2.0 |
| *Lockie et al. (9) | 250 (all VV) | N/A | N/A | N/A | 16.4 (31.7) | N/A | N/A | N/A | N/A |
| *Hunsicker et al. (10) | 444 (all VV) | N/A | N/A | N/A | 11.0 (69.4) | N/A | N/A | N/A | N/A |
| Lorusso et al. (11) | 6,834 (all VV) | N/A | N/A | 7.2 (76.3) | 3.8 (78.5) | 1.7 (73.0) | 1.2 (54.1) | N/A | N/A |
N/A, not applicable; ECMO, extracorporeal membrane oxygenation; ICH, intracranial hemorrhage; AIS, acute ischemic stroke; HIBI, hypoxic-ischemic brain injury; BD, brain death; VV, venovenous; VA, venoarterial.
*Study investigated only the incidence of ICH among patients on VV ECMO.