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. 2021 Sep 29;8:720144. doi: 10.3389/fmed.2021.720144

Table 1.

Clinical features, laboratory indicators, and initial treatment regimens in patients with Kimura disease and different diameters of tumors.

Characteristics All (n = 33) Tumor diameter <3 cm (n = 15) Tumor diameter ≥3 cm (n = 18) P value
Age (year) 391 ± 7 441 ± 8 351 ± 6 0.147
Gender (%) 0.790
   Males 28 (84.8) 13 (86.7) 15 (83.3)
   Females 5 (15.2) 2 (13.3) 3 (16.7)
BMI (kg/m2) 24.753 ± 0.64 24.293 ± 0.18 25.134 ± 0.03 0.513
Blood pressure
   SBP (mmHg) 1261 ± 3 1301 ± 1 1231 ± 4 0.120
   SDP (mmHg) 829 ± 851 ± 0 798 ± 0.069
Heart rate (bp/min) 789 ± 795 ± 771 ± 2 0.601
Tumor diameter (cm) 4.042 ± 0.50 2.050 ± 0.38 5.692 ± 0.29 <0.001
Lesion site (%) 0.427
   Parotid gland 10 (30.3) 5 (33.3) 5 (27.8)
   Neck 9 (27.3) 3 (20.0) 6 (33.3)
   Submandibular space 7 (21.2) 3 (20.0) 4 (22.2)
   Face 4 (12.1) 3 (20.0) 1 (5.6)
   Limb 2 (6.0) 0 [0] 2 (11.1)
   Lymphadenopathy 1 (3.0) 1 (6.7) 0 (0)
Lesion number (%) 0.805
   Single 6 (18.2) 3 (20.0) 3 (16.7)
   Multiple 27 (81.8) 12 (80.0) 15 (83.3)
Symptom (%) 0.095
   Skin itch 9 (27.3%) 2 (13.3) 7 (38.9)
   Fever 4 (12.1%) 1 (6.7) 3 (16.7)
   Thirst 3 (15%) 1 (6.7) 2 (11.1)
   Hoarseness 1 (6.7) 1 (6.7) 0 (0)
   Blurred vision 2 (6%) 1 (6.7) 1 (5.6)
Laboratory indicators
   Leukocyte (109/L) 8.252 ± 0.44 7.362 ± 0.05 8.992 ± 0.54 0.055
   Eosinophil (109/L) 0.210 ± 0.19 0.140 ± 0.09 0.260 ± 0.23 0.061
   Elective CRP (%) 2 (6.1%) 0 (0) 2 (11.1) 0.183
   Elective ESR (%) 1 (3%) 1 (6.7) 0 (0) 0.266
Initial treatment regimens 0.417
   Single surgery 18 (54.5%) 8 (53.3%) 10 (55.5%)
   Single prednisone 7 (21.2%) 2 (13.3%) 5 (27.8%)
   Combined therapy 8 (24.3%) 5 (33.3%) 3 (16.7%)

BMI, body mass index; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; SBP, systolic blood pressure; SDP, systolic double products.