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. 2021 Feb 24;24(4):542–546. doi: 10.4103/aian.AIAN_721_20

Table 1.

Five electrophysiological criteria for the diagnosis of childhood Guillain Barre Syndrome

Parameters Ho et al. Hadden et al. Dutch et al. Hughes et al. Rajabally et al.
AIDP
 MCV <90% LLN <90% LLN <70% LLN <90% LLN <70% LLN
<85% if D-amp <50% <85% if d-amp <50% <85% if d-amp <50%
 DL >110% ULN >110% ULN >150% ULN >110% ULN >150% ULN
>120% if D amp <LLN >120% if d-amp <LLN >120% if d-amp <LLN
 TD Unequivocal Not considered D-P duration ratio >150% ULN Not considered
D duration >300% ULN
 CB Not considered P-D amp ratio < 0.5 D amp > 20% LLN Not considered P-D amp ratio < 0.5 D amp > 20% LLN <0.7 P-D amp ratio in two nerves with an additional parameter
D CMAP >10% LLN
 F wave L >120% ULN >120% ULN >150% ULN >120% ULN >120% ULN
>150% ULN if distal CMAP <50% LLN
Absent in two nerves with dCMAP >20% LLN with an additional parameter
AMAN
No AIDP No AIDP Not considered No AIDP No AIDP
 CMAP D amp <80 % LLN D amp <80 % LLN Normal SNAP D amp <80 % LLN
P-D amp ratio < 0.7
AMSAN
Not considered Not considered Not considered No AIDP Not considered
SNAP < LLN
Inexcitable
Not considered Absent D CMAP in all nerves Not considered Absent D CMAP in all nerves Absent D CMAP in all nerves
Present in only one nerve with <10% LLN Present in only one nerve with <10% LLN Present in only one nerve with <10%LLN
Equivocal
Not considered Not fitting criteria Not considered Not considered Not fitting criteria

AIDP Acute Inflammatory Demyelinating Polyneuropathy. MCV Mean Conduction Velocity, DL Distal Latency. TD Temporal Dispersion, CB Conduction Block, SNAP Sensory Nerve Action Potential, LLN Lower Limit Normal, ULN Upper Limit Normal