Table 1.
Incident ADL Disability (number and rate) by Type and Treatment Group
| Aspirin (N = 9525) | Placebo (N = 9589) | Total (N = 19 114) | |
|---|---|---|---|
| ADL disability, participants; N (%) | |||
| No ADL disability | 8749 (91.8) | 8802 (91.7) | 17 551 (91.8) |
| Any incident ADL disability | 776 (8.1) | 787 (8.2) | 1563 (8.1) |
| Rate/1000 py | Rate/1000 py | HR (95% CI) | |
| Incident ADL disability rate | 20.6 | 20.6 | 1.00 (0.91–1.10) |
| Concurrent ADL disability; N (%) | |||
| Single ADL | 535 (68.9) | 551 (70.0) | 1085 (69.5) |
| Two ADLs | 151 (19.5) | 130 (16.5) | 281 (18.0) |
| Three or more ADLs | 90 (11.6) | 106 (13.5) | 196 (12.5) |
| Total | 776 (100) | 787 (100) | 1562 (100) |
| Incident ADL disability by type; N (%)a | |||
| ADL 1 (walking across a room) | 291 (24.5) | 291 (23.9) | 582 (24.2) |
| ADL 2 (bathing) | 274 (23.1) | 289 (23.8) | 563 (23.4) |
| ADL 3 (dressing) | 264 (22.3) | 262 (21.5) | 526 (21.9) |
| ADL 4 (transferring from chair or bed) | 255 (21.5) | 258 (21.2) | 513 (21.4) |
| ADL 5 (toileting) | 65 (5.5) | 82 (6.7) | 147 (6.1) |
| ADL 6 (eating) | 37 (3.1) | 34 (2.8) | 71 (3.0) |
| Total | 1186 (100) | 1216 (100) | 2402 (100) |
Notes: Incident ADL disability (at one time point) was observed to convert in 24% of cases to persistent physical disability through confirmation 6 months later of the same ADL disability. The order of ADL disability is from most common to the least. The same order is used in subsequent tables. ADL = Activities of daily living; CI = Confidence interval.
a N = number of participants with event; each participant could lose more than one ADL at the same time.