POPDC1, POP1 |
Promoter, hypermethylation |
Colorectal carcinoma (CRC), adenomatous polyps |
Human tissues, CRC cell lines, athymic mice |
[64] |
|
Akr1b1, Hoxb4, Rasgrf2, Rassf1, Hist1h3c, Tm6sf1 |
High cumulative methylation index |
Breast cancer |
Serum, 182 women |
[20] |
|
IRX1 |
Hypomethylation |
Osteosarcoma |
2 cell lines, serum from 67 primary osteosarcoma |
[21] |
|
Genome-scale analyses of DNA methylation |
High consistency of hypermethylation across metastases |
Lethal metastatic prostate cancer |
Tissue, 71 specimens from each of 13 subjects |
[65] |
|
2481 differentially methylated regions |
CpG island, flanking regions, and CpG sparse promoters |
Prostate cancer |
17 tissues, 6 cell lines |
[66] |
|
HOP homeobox HOPX |
Promoter, hypermethylation |
Nasopharyngeal carcinoma |
443 formalin-fixed paraffin-embedded (FFPE) NPC tissues, 5 human NPC cell lines |
[67] |
|
47 genes (RDBP), 48 CpGs significant association |
Hypermethylation |
Pheochromocytoma, paraganglioma |
310 tumors were obtained from patients, 67 with metastases |
[68] |