Table 4.
Diagnostic performance of laboratory markers in the diagnosis of MIS-C. DNI, delta neutrophil index; CRP, C-reactive protein; ANC, absolute neutrophil count; ALC, absolute lymphocyte count
| Cutoff | AUC | Sensitivity (%) |
Specificity (%) |
Positive predictive value (%) | Negative predictive value (%) | |
|---|---|---|---|---|---|---|
| DNI (%) | 0.45 | 0.893 | 79.5 | 97.1 | 95.7 | 85.3 |
| CRP (mg/dL) | 5.00 | 1.00 | 99.9 | 99.9 | 98.8 | 99.9 |
| ANC (× 1000/mm3) | 4.35 | 0.870 | 84.3 | 74.5 | 72.9 | 85.4 |
| ALC (× 1000/mm3) | 1.00 | 0.863 | 54.2 | 97.2 | 99.8 | 72.9 |
| Platelet count (× 1000/mm3) | 150.00 | 0.715 | 30.1 | 97.2 | 96.2 | 63.5 |
DNI delta neutrophil index, CRP C-reactive protein, ANC absolute neutrophil count, ALC absolute lymphocyte count