Figure 2.
Relationship between MMP7/CXCL16 expression and therapeutic response of TNBC. (A) Expression levels of MMP7 mRNA in TCGA breast cancer database were evaluated according to molecular types (TCGA) (*, P<0.05). (B) Expression levels of CXCL16 mRNA in TCGA breast cancer database were evaluated according to molecular types (*, P<0.05). (C) Expression levels of MMP7 mRNA in paired TNBC and adjacent normal tissues were evaluated by qRT-PCR. Statistical analysis was performed in no response cases (**, P<0.01). (D) Expression levels of CXCL16 mRNA in paired TNBC and adjacent normal tissues were evaluated by qRT-PCR. Statistical analysis was performed in no response cases (**, P<0.01). mRNA, messenger RNA; TNBC, triple-negative breast cancer; qRT-PCR, quantitative real-time reverse transcription polymerase chain reaction; TCGA, The Cancer Genome Atlas.