Table 1.
Demographic characteristics and medical history data of the study population at baseline.
| CD patients (n = 31) | Controls (n = 124) | p-value | |
|---|---|---|---|
| Age* (years) | 74.0 (64.5, 79.0) | 72.0 (64.0, 80.0) | 0.856 |
| Male sex* | 14 (45.2%) | 55 (44.4%) | > 0.999 |
| Comorbidities** | |||
| Total number | 0.461 | ||
| 0 | 3 (9.7%) | 11 (8.9%) | |
| 1 | 3 (9.7%) | 27 (21.8%) | |
| 2 | 9 (29.0%) | 39 (31.5%) | |
| 3 | 7 (22.6%) | 26 (21.0%) | |
| 4 | 6 (19.4%) | 16 (12.9%) | |
| ≥ 5 | 3 (9.7%) | 5 (4.0%) | |
| Cardiovascular diseases | |||
| Hypertension* | 20 (64.5%) | 82 (66.1%) | > 0.999 |
| Ischemic cardiopathy | 1 (3.2%) | 6 (4.8%) | > 0.999 |
| Chronic heart failure | 8 (25.8%) | 12 (9.7%) | 0.031 |
| Atrial fibrillation/flutter | 9 (29.0%) | 7 (5.6%) | < 0.001 |
| Stroke | 2 (6.5%) | 8 (6.5%) | > 0.999 |
| Pacemaker | 1 (3.2%) | 0 (0.0%) | 0.200 |
| Respiratory diseases | |||
| Asthma | 1 (3.2%) | 9 (7.3%) | 0.688 |
| COPD | 8 (25.8%) | 18 (14.5%) | 0.216 |
| Metabolic diseases | |||
| Diabetes mellitus* | 10 (32.3%) | 40 (32.3%) | > 0.999 |
| Obesity (BMI > 30) | 1 (3.2%) | 10 (8.1%) | 0.695 |
| Other conditions | |||
| Cirrhosis | 0 (0.0%) | 2 (1.6%) | > 0.999 |
| Psychiatric condition | 1 (3.2%) | 9 (7.3%) | 0.688 |
| Chronic renal disease | 0 (0.0%) | 3 (2.4%) | > 0.999 |
| Dyslipidemia | 0 (0.0%) | 1 (0.8%) | > 0.999 |
| HIV | 0 (0.0%) | 2 (1.6%) | > 0.999 |
| Neoplasia | 3 (9.7%) | 8 (6.5%) | 0.461 |
| Transplantation | 1 (3.2%) | 3 (2.4%) | > 0.999 |
| Dementia | 0 (0.0%) | 1 (0.8%) | > 0.999 |
| Epilepsy | 0 (0.0%) | 0 (0.0%) | – |
| Toxic habits | |||
| Alcohol | 1 (3.2%) | 6 (4.8%) | > 0.999 |
| Tobacco (active or former) | 7 (22.6%) | 35 (28.2%) | 0.684 |
Numbers are presented are medians (P25-P75) or counts (percentages).
BMI body mass index, CD Chagas disease, COPD chronic obstructive pulmonary disease.
*Controls were paired for age, sex, hospital, hypertension and diabetes.
**This variable does not include Chagas disease.