Table 1.
Cross-reaction study information and results (+ or −). Viruses were purified viral culture preparations (concentration) or supernatants (dilution) and bacteria were culture suspensions inactivated by heating. Bacterial concentration of 4 × 107 bct/mL (OD600 = 0.04) in reaction was based on that OD600 = 1.0 corresponds to 109 bct/mL.
| Analyzed microbe | Source | Reaction concentration | Result |
|---|---|---|---|
| Human coronavirus OC43 ATCC VR1558 | ATCC | 5 × dilution | − |
| Human coronavirus 229E ATCC VR740 | − | ||
| Human coronavirus NL63 | Academic Medical Center, Amsterdam, the Netherlands | − | |
| SARS coronavirus 1 (purified nucleoprotein) | ArcDia International Ltd, Finland | 1 µg/mL | + |
| MERS coronavirus (purified nucleoprotein) | 1 µg/mL | − | |
| Human coronavirus HKU1 (purified nucleoprotein) | 10 µg/mL | − | |
| Influenza A virus H3N2 A/Panama/2007/99 | Hytest Ltd, Turku, Finland | 5 µg/mL | − |
| Influenza A virus H3N A/Texas/50/12 | Research Institute of Influenza, St Petersburg, Russia | 10 µg/mL | − |
| Influenza A virus H3N2 A/Victoria/361/11 | 10 µg/mL | − | |
| Influenza B virus Phuket/3073/2013 | 100 × dilution | − | |
| Influenza A virus H1N1 A/New Caledonia/20/99 | Biomarket Ltd, Turku Finland | 5 µg/mL | − |
|
Influenza A virus (so-called swine flu) H1N1v A/FIN/554/09 |
Finnish institute for health and welfare | 40 × dilution | − |
| Respiratory syncytial virus type A / Long | AbD Serotec Inc, now Bio-Rad Laboratories, Inc | 7.4 × dilution | − |
| Respiratory syncytial virus type B / clinical strain (EQAS round 1, 2017) | Labquality Ltd, Helsinki, Finland | 2 × dilution | − |
| Human metapneumovirus | Department of Virology, University of Turku, Finland | 10 × dilution | − |
| Parainfluenza 2 virus | 25 × dilution | − | |
| Human bocavirus (clinical specimen) | Turku University Hospital, Finland | Nasopharyngeal swab suspended in 1.3 mL | − |
| Human bocavirus (purified VP2 antigen) | Vilnius University, Institute of Biotechnology, Lithuania | 5 µg/mL | − |
| Parainfluenza 1 virus Sendai | Hytest Ltd, Turku, Finland | 50 µg/mL | − |
| Parainfluenza 3 virus Washington/1957 C243 | AbD Serotec Inc, now Bio-Rad Laboratories, Inc | 20 µg/mL | − |
| Adenovirus strain 6 | Hytest Ltd, Turku, Finland | 4 µg/mL | − |
| Streptococcus pneumoniae ATCC 49619 | Finnish institute for health and welfare | 4 × 107 bacteria/mL | − |
| Streptococcus pyogenes ATCC 19615 | − | ||
| Staphylococcus aureus ATCC 29213 | − | ||
| Staphylococcus epidermidis (isolate) | − | ||
| Streptococcus anginosus (209) | − | ||
| Streptococcus constellatus (5690 | − | ||
| Streptococcus intermedius (1343) | − | ||
| Haemophilus influenzae ATCC 33391 | − | ||
| Haemophilus parainfluenzae ATCC 33392 | − |