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. 2021 Oct 13;4:1196. doi: 10.1038/s42003-021-02728-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — The procedures were identical to the methods used in animal serum neutralization analyses. a Mean neutralization ID₅₀ values of different SARS-CoV-2 infected convalescence serum samples against pseudotyped SARS-CoV-2 variants. Red to blue indicates increased neutralization activity high to low as shown in the scale bar. b the ID₅₀ ratios, compared with the D614G reference strain, are displayed using dot plots. c the ID₅₀ ratios, compared with the B.1.1.7 variant, are displayed using dot plots. d the ID₅₀ ratios, compared with the B.1.351 variant, are displayed using dot plots. Data are presented as means ± SEMs. Dashed lines indicate the threshold of fourfold difference. The experiments were repeated twice due to the sample limitation. e ID₅₀ ratios of sera from inactived-vaccine, compared with the D614G reference strain, are displayed using dot plots. f ID₅₀ ratios of sera from adenovirus-vaccine, compared with the D614G reference strain, are displayed using dot plots. b-f, data are presented as means ± SEMs. Asterisks indicate statistical significance.