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. 2021 Oct 13;11:20332. doi: 10.1038/s41598-021-98684-4

Table 5.

The influence of stress on depression as a function of depressive symptoms PGS.

b se t pr. <  min max
Age (years) 0.004 0.005 0.730 0.465 − 0.006 0.014
Sex (male)
 Female 0.053 0.020 2.700 0.007 0.015 0.092
Race-ethnicity (NH White)
 NH Black − 0.142 0.160 − 0.890 0.374 − 0.457 0.172
 Native American 0.050 0.222 0.220 0.822 − 0.385 0.485
 Asian 0.020 0.136 0.140 0.885 − 0.247 0.287
 Hispanic 0.024 0.064 0.370 0.709 − 0.102 0.150
Education (< high school)
 High school − 0.227 0.063 − 3.610 0.000 − 0.350 − 0.104
 Some college − 0.237 0.059 − 4.000 0.000 − 0.353 − 0.121
 College graduate − 0.275 0.060 − 4.560 0.000 − 0.393 − 0.157
 Post baccalaureate − 0.277 0.063 − 4.410 0.000 − 0.399 − 0.154
Stress (0–5) 0.179 0.012 15.360 0.000 0.156 0.202
PGS depressive symptoms − 0.009 0.012 − 0.730 0.467 − 0.033 0.015
Stress*PGS 0.000 0.011 0.010 0.991 − 0.022 0.022
Genetic ancestry
 PC1 0.053 0.063 0.840 0.403 − 0.071 0.176
 PC2 0.026 0.027 0.970 0.332 − 0.027 0.079
 PC3 − 0.020 0.018 − 1.130 0.260 − 0.054 0.015
 PC4 0.003 0.011 0.260 0.793 − 0.019 0.025
 PC5 0.000 0.009 − 0.040 0.969 − 0.019 0.018
Intercept 1.492 0.198 7.550 0.000 1.104 1.879

Stress*PGS is boldfaced to highlight. Reference category in brackets. Cell entries are as follows: b = unstandardized OLS regression estimates; se = standard error; t = test statistic; pr. ≤  two-tailed p-values; min and max = boundaries of the 95% confidence intervals. All data are weighted to reflect the design of the Add Health Study.