Table 4.

Some relevant data between the experimental and the controlled group in the included literature.

		Dosage regimen design	Dose of norepinephrine at baseline (ug/kg/min)	Dose of Norepinephrine at 24 h (ug/kg/min)	Fluid input (ml)	Urinary output (ml)
Morelli 72005	Experimental Group	Levosimendan (0.2 μg/kg/min) for 24 h	0.22 ± 0.07	0.22 ± 0.06	5907 ± 330	2028 ± 461
	Controlled Group	Dobutamine (5 μg/kg/min) for 24 h	0.22 ± 0.05	0.23 ± 0.06	4311 ± 136	1521 ± 302
	P value		NA	NA	< 0.05	< 0.05
Morelli 142010	Experimental Group	Levosimendan (0.2 μg/kg/min) for 24 h	0.4 (0.2–0.9)	0.3 ( 0.1–0.9 )	NA	NA
	Controlled Group	Dobutamine (5 μg/kg/min) for 24 h	0.4 (0.3–0.7)	0.4 ( 0.3–1.1 )	NA	NA
	P value		0.72	0.10	NA	NA
Fang15 2014	Experimental Group	Levosimendan (0.2 μg/kg/min) for 24 h after dobutamine (5 μg/kg/min) for 48 h	NA	0.33 ± 0.06	5746.6 ± 420.0	2213.4 ± 354.0
	Controlled Group	Dobutamine (5 μg/kg/min) for 48 h	NA	0.33 ± 0.05	4156.7 ± 215.0	1533.8 ± 402.0
	P value		NA	0.909	0.000	0.000
Meng16 2016	Experimental Group	Levosimendan (0.2 μg/kg/min) for 24 h	0.42 ± 0.13	0.36 ± 0.11	NA	NA
	Controlled Group	Dobutamine (5 μg/kg/min) for 24 h	0.40 ± 0.11	0.37 ± 0.09	NA	NA
	P value		0.619	0.761	NA	NA
Hajjej17 2017	Experimental Group	Levosimendan (0.2 μg/kg/min) for 24 h	0.3 (0.1–0.8)	0.34 (0.2–0.9)	997 (842–1200)	NA
	Controlled Group	Dobutamine (5 μg/kg/min) for 24 h	0.2 (0.1–0.7)	0.27 (0.1–0.6)	898 (778–1120)	NA
	P value		NA	NA	-	NA
Xu18 2018	Experimental Group	Levosimendan (0.2 μg/kg/min) for 24 h	23.3 ± 3.6	NA	2741 (2499–4144)	985 (530–1740)
	Controlled Group	dobutamine (5 μg/kg/min) for 24 h	23.9 ± 7.4	NA	2740 (2524–3050)	1720 (1195–2400)
	P value		0.591	NA	NA	NA

NA Not available in the included literature.