Table 1.
Non-GBA (n = 5) | GBA (n = 4) | p-value | |
---|---|---|---|
Age (years) | 60.0 (7.1) | 54.0 (8.5) | 0.29 |
Disease duration (years) | 9.4 (4.2) | 6.3 (2.9) | 0.19 |
Sex | M, 4; F, 1 | M, 3; F, 1 | |
Ethnicity (n) | 2 | 3 | |
Caucasian, non-Hispanic | 1 | 1 | |
Caucasian, Hispanic | 2 | 0 | |
Asian | 0 | 0 | |
Other | |||
MDS-UPDRS Part III (OFF medication) | 51.8 (13.6) | 47.3 (8.3) | 1.0 |
MDS-UPDRS Part III (ON medication) | 22.6 (5.3) | 29.8 (10.5) | 0.41 |
Bradykinesia asymmetry score | −0.6 (3.5) | 7.0 (2.9) | 0.01 |
Left STN | |||
X | −10.6 (1.4) | −9.7 (1.7) | 0.56 |
Y | −4.8 (1.0) | −4.3 (0.7) | 0.41 |
Z | −5.0 (0.8) | −4.8 (0.9) | 1.0 |
Right STN | |||
X | 10.5 (1.0) | 9.2 (0.2) | 0.06 |
Y | −3.7 (1.6) | −4.4 (0.4) | 0.19 |
Z | −6.3 (1.0) | −5.4 (1.0) | 0.19 |
Mean values (standard deviation) are shown; MDS-UPDRS, Movement Disorders Society Unified Parkinson's Disease Rating Scale; STN, subthalamic nucleus; GBA, Glucocerebrosidase; M, male; F, female.