TABLE 2.
Cytosolic and nuclear Fe/S cluster assembly components.
| Complex | Human | Yeast | Function | Location |
| CIA complex | CFD1 | Cdf1 | Scaffold protein | Cytoplasm |
| NBP35 | Nbp35 | Scaffold protein | Cytoplasm and nucleus | |
| CIAPIN1 | Dre2 | Electron donor | Cytoplasm and nucleus | |
| NDOR1 | Tah18 | Electron donor | Cytoplasm | |
| IOP1 | Nar1 | Adaptor protein of CIA complex | Cytoplasm | |
| CIA1 | Cia1 | Transfer and insert Fe–S clusters into target proteins | Cytoplasm | |
| CIA2B | Cia2 | Transfer and insert Fe–S clusters into target proteins | Cytoplasm and nucleus | |
| MMS19 | Met18 | Transfer and insert Fe–S clusters into target proteins | Cytoplasm and nucleus | |
| CIA2A | Absent | Specific maturation factor of IRP1 | Cytoplasm |