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. 2021 Sep 30;12:729768. doi: 10.3389/fgene.2021.729768

Table 2.

Association of MIAT expression with clinicopathological features.

Clinicopathological parameters studies (n) Patients (n) OR (95% CI) P-value Heterogeneity (I2, P) Model
Age (elderly vs. non-elderly) 1,506 1.07 (0.87, 1.32) 0.516 0.0%, 0.995 Fixed
Gender (male vs. female) 1,418 0.95 (0.77, 1.19) 0.668 0.0%, 0.799 Fixed
Tumor size (large size vs. small size) 814 2.26 (1.34, 3.81) 0.002 63.8%, 0.003 Random
Distant metastasis (presence vs. absence) 1,006 2.54 (1.84, 3.50) <0.001 19.1%, 0.289 Fixed
TNM stage (III + IV vs. I + II) 1,262 2.38 (1.36, 4.18) 0.002 75.3%, <0.001 Random
Lymph node metastasis (positive vs. negative) 1,145 2.59 (1.25, 5.36) 0.011 83.2%, 0.000 Random
Differentiation grade (poorly and moderately vs. well) 229 2.65 (1.54, 4.58) <0.001 0.0%, 0.732 Fixed
Histology (adenocarcinoma vs. other types) 396 0.72 (0.48, 1.10) 0.128 0.0%, 0.807 Fixed