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. 2021 Sep 30;12:731048. doi: 10.3389/fimmu.2021.731048

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Copyright © 2021 Xu, Tang, Liu, Luo and Cheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Risk signature was associated with the prognosis of LGG patients. (A) Nomogram model of grade, age, and risk score in the TCGA dataset. (B) Calibration curve model to verify the predictive value of risk score regarding 3-year and 5-year survival. (C) Kaplan-Meier analysis of high-score and low-score in LGG patients. (D, E) Kaplan-Meier analysis of high-score and low-score patients in grade II (D) and grade III (E) gliomas. (F, G) Kaplan-Meier analysis of high-score and low-score patients in IDH wildtype (F) and IDH mutant (G) gliomas. (H, I) Kaplan-Meier analysis of high-score and low-score patients ≤45 years old (H) or >45 years old (I) in diffuse gliomas.