Table 1.

Image brightness, contrast, and timing for each CLE optical biopsy by FNa dosing groups.

FNa Group:CLE biopsy no.	Brightness*	Contrast*	Time after FNa dose, min
Redose
1	88.2	33.2	5
2	95.0	25.2	10
3	88.7	31.2	15
4	72.9	26.8	3
5	76.8	34.6	5
6	51.2	31.7	5
7	51.1	23.0	5
8	78.7	29.6	5
9	76.7	39.9	5
10	73.2	27.5	3
11	97.8	28.3	2
12	89.2	29.5	10
Initial dose
1	52.8	25.2	13
2	53.4	25.1	180
3	71.0	26.0	150
4	64.0	24.4	60
5	60.4	28.5	65
6	55.5	29.2	70
7	54.1	21.3	60
8	61.3	26.2	60
9	72.3	28.3	70
10	57.8	25.8	90
11	60.4	26.7	120
12	85.6	27.0	60
13	88.7	25.6	60
14	93.7	25.1	60
15	91.2	27.7	60
16	89.0	25.3	90
17	70.2	24.9	90
18	77.8	19.6	105
Single dose
1	60	27.4	180
2	52	24.6	180
3	61	26.8	180
4	43	15.1	120
5	65	21.8	120
6	52.9	17	120
7	74.1	23.6	120
8	24.2	9.8	90
9	24	11.7	90
10	15.1	6.8	110
11	32.6	12.9	170
12	53.4	25.7	90
13	51.3	20.6	110
14	50.8	18.9	180
15	63.3	26.2	90
16	67.8	24.7	90
17	68.8	25.5	90
18	71	27	90
19	66	25	120

*Values are reported in units of optical density defined by Fiji open-source analytic software. Brightness is the mean gray value, calculated by the sum of the gray values of all the pixels in the selection divided by the number of pixels, and contrast is the standard deviation of gray values used to generate the mean.