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. 2021 Oct 6;2021:8774663. doi: 10.1155/2021/8774663

Figure 3.

Figure 3

Delayed inhibition of TRPM2 with tatM2NX restores synaptic plasticity. (a) Time course of fEPSP slope 14 days after sham mice were treated on day 13 with 20 mg/kg tatSCR (black) or tatM2NX (red) and 14 days after CA/CPR mice were treated on day 13 with 20 mg/kg tatSCR (blue) or tatM2NX (green). (b) Quantification of change in fEPSP slope 60 minutes after TBS stimulation normalized to 20 minutes of baseline recording (set at 100%). Each point represents one hippocampal slice, with no more than 2 slices from an individual mouse. ∗p < 0.05 by one-way ANOVA.