Table 4.
Demographics and glutathione levels of responders (n = 12) and non-responders (n = 7).
| Characteristics of responders and non-responders in the CRWP group | Responders (n = 12) | Non-responders (n = 7) | p-value |
|---|---|---|---|
| Age (mean + SEM) | 4.23 ± 0.22 | 3.48 ± 0.18 | 0.03* |
| Parent information (mean + SEM) | |||
| Paternal age at child's birth (years) | 34.3 ± 3.84 | 39.5 ± 5.2 | 0.45 |
| Maternal age at child's birth (years) | 33.1 ± 2.47 | 36.9 ± 3.0 | 0.35 |
| Baseline glutathione levels | |||
| tGSH (uM/105 WBC) | 144.8 ± 21.4 | 65.6 ± 11.7 | 0.01* |
| GSH (uM/105 WBC) | 127.8 ± 19.8 | 51.27 ± 9.9 | 0.01* |
| Change in glutathione | |||
| tGSH (uM/105 WBC) | 4.60 ± 6.7 | 6.49 ± 4.0 | 0.83 |
| GSH (uM/105 WBC) | 3.68 ± 5.6 | 4.17 ± 3.7 | 0.95 |
*
Significant difference between placebo and non-responder subgroups where p <0.05.
CRWP, cysteine-rich whey protein; SEM, standard error of the mean; WBC, white blood cells; GSH, glutathione (active, reduced form); GSSG, glutathione (inactive, oxidized form); tGSH, total glutathione.