Table 5.

Changes in VABS-II scores in responders, non-responders, and placebo groups.

Vineland adaptive behavior scale	Responders (n = 12)	Non-responders (n = 7)	Placebo (n = 21)	P-value responders vs. non-responders	P-value responders vs. placebo
Adaptive behavior composite standard score	6.5 ± 1.32	−2.86 ± 0.91	0.00 ± 1.25	<0.0001†	0.0003†
Communication standard total score	7.67 ± 2.55	−1.71 ± 2.40	−0.29 ± 2.20	0.008†	0.01†
Receptive V-scale score	1.58 ± 0.69	−0.86 ± 0.59	0.48 ± 0.93	0.01†	0.21
Expressive V-scale score	1.67 ± 0.63	−0.29 ± 0.60	0.62 ± 0.54	0.03†	0.08
Written V-scale score	0.64 ± 0.47	0.29 ± 0.52	−0.29 ± 0.49	0.32	0.12
Daily living skills standard total score	4.83 ± 2.31	−2.7 ± 1.6	−1.00 ± 1.39	0.008†	0.007†
Personal V-scale score	2 ± 0.71	−0.14 ± 0.77	−0.05 ± 0.36	0.03†	0.004†
Domestic V-scale score	−0.08 ± 0.57	−0.71 ± 0.60	0.05 ± 0.63	0.23	0.45
Community V-scale score	0.33 ± 0.45	−0.43 ± 0.62	−0.05 ± 0.51	0.19	0.20
Socialization standard total score	6.67 ± 3.04	−0.43 ± 2.17	−0.81 ± 2.06	0.04†	0.02†
Interpersonal relationships V-scale score	0.83 ± 0.82	0.29 ± 0.57	−0.38 ± 0.59	0.30	0.12
Play and leisure time V-scale score	0.92 ± 0.58	−0.43 ± 0.37	−0.38 ± 0.44	0.03†	0.04†
Coping skills V-scale score	2.58 ± 1.18	−0.15 ± 0.51	−0.24 ± 0.89	0.03†	0.04†
Motor skills standard total score	5.33 ± 2.32	−6.86 ± 4.4	1.33 ± 2.56	0.02†	0.05
Gross V-scale score	0.5 ± 0.57	−2.29 ± 0.92	−0.14 ± 0.60δ	0.01†	0.09
Fine V-scale score	1.33 ± 0.54	0 ± 0.62	0.57 ± 0.39	0.07	0.13
Maladaptive behavior total v-scale score	−1.42 ± 0.47	1.0 ± 0.84	1.26 ± 1.05	0.01†	0.003†
Internalizing V-scale score	−1.33 ± 0.64	0 ± 0.37	0.37 ± 0.22	0.04†	0.0003†
Externalizing V-scale score	−1.33 ± 0.51	1.17 ± 1.20	1.26 ± 1.08	0.02†	0.008†

^†p <0.05, one-tail t-test.

^δSignificant difference between placebo and non-responder subgroup where p <0.05.

VABS-II, Vineland Adaptive Behavior Scale, 2nd edition. Values are mean ± SEM.