Table 4.
Age, gender, renal parameters, proteinuria, erythrocyturia, fibrosis, crescents, age of transplantation, blood pressure, BMI, weight, and height at the time of renal biopsy in two groups of patients with original diagnosis of IgAN after kidney transplant with graft failure.
| Slow progressors (group 1) | Rapid progressors (group 2) | p value | |
|---|---|---|---|
| N | 17 | 33 | |
| Age at RB, years | 33.5 (9.9) | 34.9 (12.3) | 0.49 |
| Patient gender, male, n (%) | 11 (65%) | 27 (82%) | 7.8* |
| Creatinine at RB (μmol/L) | 330 (184) | 399 (277) | 0.633 |
| eGFR CKD EPI (mL/s) | 0.47 (0.36) | 0.48 (0.46) | 0.739 |
| PU at RB (g/24 hours) | 1.52 (1.72) | 2.93 (2.88) | 0.077 |
| Erythrocyturia at RB, n (%) | 15 (88%) | 23 (74%)2 | 8.1* |
| Fibrosis at RB, n (%) | 11 (79%)3 | 22 (85%)7 | 7.9* |
| Crescents at RB, n (%) | 4 (29%)3 | 17 (59%)4 | 6.1* |
| Age of transplantation, years | 40 (10) | 37 (12) | 0.325 |
| SPB RB | 155 (29) | 144 (19) | 0.285 |
| DPB RB | 99 (22) | 86 (18) | 0.208 |
| BMI RB | 24 (3) | 26 (4) | 0.033 |
| Weight RB (kg) | 73 (10) | 78 (19) | 0.105 |
| Height RB (cm) | 174 (11) | 171 (8) | 0.632 |
*Test of proportion; calculated Z value (normal distribution) from transformed binomial distribution; Z (p = 0.05) = 1.96.
Numbers in superscript indicate number of missing values.
eGFR, glomerular filtration rate (ml/s); PU, proteinuria (g/day); SBP, systolic blood pressure; DBP, diastolic blood pressure; RB, renal biopsy of native kidney; BMI, body mass index.
Quantitative parameters: mean (SD); qualitative parameters: group frequency (%).