Table 3.
Clinicopathological characteristics and MET amplification.
| Pathological characteristics | Total number (%) | MET amplification (%) | MET amplification WT (%) | P value (Amp vs Amp WT) |
|---|---|---|---|---|
| Age | 2,951 | 23 | 2,928 | 0.318 a |
| >60 years old | 1,490 (50.49) | 14 (9.40) | 1,476 (90.60) | |
| ≤60 years old | 1,461 (49.51) | 9 (0.62) | 1,452 (99.38) | |
| Sex | 2,951 | 23 | 2,928 | 0.104 a |
| Male | 1,302 (44.12) | 14 (1.08) | 1,288 (98.92) | |
| Female | 1,649 (55.88) | 9 (0.55) | 1,640 (99.45) | |
| AJCC tumor stage | 2,860 | 23 | 2,837 | 0.000 a ,* |
| 0+I+II | 2,321 (81.15) | 10 (0.43) | 2,311 (99.57) | |
| III+IV | 539 (18.85) | 13 (2.41) | 526 (97.59) | |
| Tumor location | 2,880 | 23 | 2,857 | 0.058 a |
| Left | 1,185 (41.15) | 5 (0.42) | 1,180 (99.58) | |
| Right | 1,695 (58.85) | 18 (1.06) | 1,677 (98.94) | |
| Pleural invasion | 2,356 | 10 | 2,346 | 0.780 a |
| Yes | 434 (18.42) | 1 (0.23) | 433 (99.77) | |
| No | 1,922 (81.58) | 9 (0.47) | 1,913 (99.53) | |
| Smoke | 2,945 | 21 | 2,924 | 0.492 a |
| Ever | 918 (31.17) | 8 (0.87) | 910 (99.13) | |
| Never | 2,027 (68.83) | 13 (0.64) | 2,014 (99.36) | |
| Histology type | 2,927 | 23 | 2,904 | 1.000 a,# |
| Adenocarcinoma | 2,676 (91.42) | 21 (0.78) | 2,655 (99.22) | |
| Squamous cell carcinoma | 187 (6.39) | 2 (1.07) | 185 (98.93) | |
| Other types | 64 (2.19) | 0 (0.00) | 64 (100.00) |
a
Pearson’s chi-squared test; #Significance between adenocarcinoma and squamous cell carcinoma.
*Statistically significant.
MT, Mutant; WT, Wildtype; Amp, Amplification.
bold values indicate the number of total patients in each clinical characters that were analyzed.