TABLE 1.
Meta-analysis study characteristics.
| AD |
CN |
||||||
| Study | Accession | Total participants | AD, no. (%) | Female/Male (% Female) | APOE ε4 Carrier Yes/No (% Yes) | Female/Male (% Female) | APOE ε4 Carrier Yes/No (% Yes) |
| Brain Transcriptomic Studies | |||||||
| Allen | https://aging.brain-map.org/ | 212 | 72 (34) | 29/43 (40) | 22/50 (31) | 54/86 (39) | 19/121 (14) |
| Mayo Clinic RNA-Seq | syn5550404 | 154 | 80 (52) | 49/31 (61) | 42/38 (53) | 36/38 (49) | 9/65 (12) |
| MSBB | syn3159438 | 301 | 185 (62) | 131/54 (71) | 63/122 (34) | 57/59 (49) | 16/100 (13) |
| ROSMAP | syn3219045 | 417 | 218 (52) | 151/67 (70) | 83/135 (38) | 122/77 (61) | 33/166 (17) |
| Sum | 1084 | 555 (52) | 360/195 (65) | 210/345 (38) | 269/260 (51) | 77/452 (15) | |
| Whole Blood Transcriptomic Studies | |||||||
| ADNI | http://adni.loni.usc.edu/ | 301 | 43 (14) | 17/26 (40) | 32/11 (74) | 135/125 (52) | 71/189 (27) |
| AddNeuroMed1 | GSE63060 | 182 | 91 (50) | 65/26 (71) | 52/39 (57) | 55/36 (60) | 30/61 (33) |
| AddNeuroMed2 | GSE63061 | 160 | 86 (43) | 59/27 (69) | 47/39 (55) | 45/29 (61) | 15/59 (20) |
| Sum | 645 | 220 (34) | 141/79 (64) | 131/89 (60) | 235/190 (55) | 116/309 (27) | |