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. 2021 Sep 30;11:754094. doi: 10.3389/fonc.2021.754094

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Copyright © 2021 Barbosa, Pinto, Peixoto, Guerra, Pinheiro, Santos, Pinto, Escudeiro, Bartosch, Santos, Brandão, Silva and Teixeira

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Concordance of variants calls between tumor and plasma samples from the patient treatment naïve group. In patients with more than one somatic variant identified, the VAF for variants shared between matched tumor and plasma samples shows a concordance in hierarchy of VAF in three samples (OC05, OC28 and OC89).