Figure 1.

The m⁶A RNA levels of peripheral blood immune cells in CRC patients and NCs. (A) The m⁶A levels of peripheral blood RNA in NCs (n = 64) and CRC patients (n = 105). (B) The m⁶A levels of peripheral blood RNA at different clinical stages of CRC patients (stage I, n = 6; stage II, n = 20; stage III, n = 31; stage IV, n = 26). (C) Comparison of m⁶A levels of peripheral blood RNA between CRC patients with (n = 26) and without (n = 57) metastasis. (D) Comparison of m⁶A levels of peripheral blood RNA between CRC patients with (n = 70) and without (n = 105) treatment. (E) The m⁶A levels of peripheral blood RNA in CRC patients (n = 33) before and after 14 days of treatment. Bars represent the mean ± SD of the results from replicate measurements; *p < 0.05, **p < 0.01 and ***p < 0.001.