Time	Events
Admission	Malaise, dyspnoea, and cough over 2 days Severe acute respiratory syndrome coronavirus 2 + (nasal swap) Remdesivir and dexamethason
Day 5 after admission	Acute coronary syndrome and cardiogenic shock Coronary angiography w/o conclusive explanation (chronic thrombotic occlusion of the marginal branches of the left coronary artery circumflex branch) Echo: severely reduced biventricular function [left ventricular ejection fraction (LVEF) 15%], with global hypo-/to akinesia
Day 7 [Day 2 intensive care unit (ICU)]	Neurological symptoms Thrombocytopenia, acute kidney injury, and haemolytic anaemia with schistocytes → suspicion of thrombotic thrombocytopenic purpura/thrombotic microangiopathy
Day 8 (Day 3 ICU)	Begin renal replacement therapy (RRT), steroid pulse, and therapeutic plasma exchange (TPE)
Day 15 (Day 10 ICU)	7th TPE sessions without improvement
Day 16 (Day 11 ICU)	Eculizumab 800 mg i.v.
Day 17 (Day 12 ICU)	Stop RRT, first day of increasing platelets, estimated glomerular filtration rate 40 mL/min
Day 18 (Day 13 ICU)	Stop inotropy
Day 19 (normal ward)	Echo: LVEF to 41%
Day 32	Complete remission/discharge (normalized platelet counts, absence of schistocytes)