Table 1.
Demographic and clinical characteristics of patients diagnosed with Alzheimer's disease (AD) and behavioral variant frontotemporal dementia (bvFTD).
| Characteristics | bvFTD (n = 31) | AD (n = 28) | |||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | p-value | |
| Women n (%) | 13 (41.90%) | 17 (60.71%) | 0.195a | ||
| Age (range: 50–87) | 66.94 | 9.26 | 74.15 | 9.22 | 0.004b |
| Schooling (0–21 Years) | 11.74 | 4.57 | 9.43 | 4.49 | 0.055b |
| Clinical characteristics | |||||
| MMSE (Baseline) | 23.61 | 4.96 | 23.35 | 3.54 | 0.397b |
| MMSE (1 Year) | 22.50 | 4.69 | 22.87 | 3.91 | 0.775b |
| 0.005 c | 0.043c | ||||
| ACER (Baseline) | 71.71 | 16.36 | 67.57 | 11.77 | 0.173b |
| ACER (1 Year) | 69.32 | 15.54 | 66.61 | 11.51 | 0.563b |
| 0.001c | 0.028c | ||||
| EXIT-25 (Baseline) | 14.96 | 9.36 | 12.43 | 7.82 | 0.353b |
| EXIT-25 (1 Year) | 16.74 | 10.28 | 12.90 | 9.04 | 0.256b |
| 0.028c | 0.753c | ||||
| IFS (Baseline) | 15.42 | 6.35 | 16.41 | 5.06 | 0.973b |
| IFS (1 Year) | 15.02 | 6.34 | 16.06 | 5.13 | 0.942b |
| 0.423c | 0.108c | ||||
| FAB (Baseline) | 12.42 | 4.07 | 13.75 | 2.69 | 0.607b |
| FAB (1 Year) | 12.35 | 4.02 | 13.60 | 2.74 | 0.386b |
| 1.00c | 1.00c | ||||
| NPI Total (Baseline) | 45.58 | 23.85 | 25.64 | 16.92 | 0.001b |
| NPI Total (1 Year) | 47.90 | 22.88 | 28.36 | 19.46 | 0.001b |
| 0.008c | 0.043c | ||||
| NPI Distress (Baseline) | 19.16 | 10.19 | 12.29 | 8.20 | 0.007b |
| NPI Distress (1 Year) | 20.13 | 9.76 | 13.11 | 8.63 | 0.006b |
| 0.005c | 0.028c | ||||
a
Chi-square Test.
b
Mann-Whitney U Test.
c
Wilcoxon Matched Pairs Test.
AD, Alzheimer's disease; bvFTD, behavioral variant frontotemporal dementia; MMSE, Mini Mental State Examination; ACE-R, Addenbrooke's Cognitive Examination-Revised; EXIT-25, Executive Interview with 25 items; IFS, INECO Frontal Screening; FAB, Frontal Assessment Battery.