Table 3.
Relationship between viral load and immunological parameters at first sampling.
| Immunological parameters | All 41 NPS | Children aged <15 years | Adults aged ≥15 years | |||
|---|---|---|---|---|---|---|
| R spearman | p-value§ | R spearman | p-value§ | R spearman | p-value§ | |
| logPRNT | 0.118 | 0.463 | 0.523 | 0.026 | 0.035 | 0.875 |
|
%CD4 activation
(CD4+HLA-DR+CD38+) |
−0.272 | 0.085 | −0.375 | 0.126 | −0.182 | 0.406 |
|
%CD8 activation
(CD8+HLA-DR+CD38+) |
−0.083 | 0.607 | −0.307 | 0.216 | 0.059 | 0.788 |
|
%B activated memory
(CD19+CD10−CD21−CD27+) |
−0.267 | 0.092 | −0.463 | 0.053 | −0.202 | 0.356 |
|
%CD4 senescence
(CD4+CD28−CD57+) |
0.077 | 0.638 | 0.197 | 0.433 | −0.023 | 0.919 |
|
%CD8 senescence
(CD8+CD28−CD57+) |
0.159 | 0.321 | −0.141 | 0.576 | 0.334 | 0.119 |
|
%B senescence
(CD19+IgD−CD27−) |
−0.173 | 0.279 | −0.358 | 0.145 | −0.197 | 0.369 |
|
%CD4 exhaustion
(CD4+PD-1+) |
−0.016 | 0.919 | −0.216 | 0.390 | 0.076 | 0.730 |
|
%CD8 exhaustion
(CD8+PD-1+) |
0.159 | 0.321 | −0.222 | 0.376 | 0.289 | 0.180 |
|
%T-regs
(CD4+CD25+CD127−FoxP3+) |
0.087 | 0.589 | 0.271 | 0.276 | 0.026 | 0.906 |
|
%B-regs
(CD19+CD24hiCD38hi) |
−0.053 | 0.744 | 0.437 | 0.070 | −0.154 | 0.483 |
§Spearman correlation.
Bold values refer to R spearman and p-values that are or tended to be significant.