Figure 1.

Microbial gut phylotypes at the family level that displayed significantly higher (Linear discriminant analysis effect size [LEfSe]) relative abundances in OVX-E2-High rats than in OVX-Vehicle rats. Statistical analysis was limited to families that had a ≥ 2% relative abundance in at least one sample. The asterisks indicate significant differences (*p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001). Solid lines between groups indicate significant q values. Dashed lines between groups indicate non-significant q values (q ≥ 0.05). Group abbreviations (e.g., Sham-Vehicle) are described in Table 1 . Error bars indicate standard deviations.