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Hypothetical model illustrating the potential impact of E2 including endogenous levels as well as different exogenous doses following ovariectomy on microbial families of the mammalian gut microbiota and their functionality. (A) From left to right, increasing or decreasing width illustrates an increase or decrease in abundance of the respective attribute (e.g., fermentation products). (B) From top to bottom, decreasing width illustrates a decrease in abundance of microbial families.
