TABLE 1.
Baseline characteristics of AD patients in the Sunnybrook Dementia Study and Alzheimer's Disease Neuroimaging Initiative by apolipoprotein E (APOE) ɛ4 status
| Characteristics | APOE ɛ4− (SDS) | APOE ɛ4− (ADNI) | APOE ɛ4+ (SDS) | APOE ɛ4+ (ADNI) | Total (SDS) | Total (ADNI) |
|---|---|---|---|---|---|---|
| n | 61 | 61 | 109 | 123 | 170 | 184 |
| Age (years) | 72.6 (9.8) | 76.4 (8.5) | 70.6 (8.7) | 74.4 (6.9) | 71.3 (9.1) | 75.1 (7.5) |
| Sex (M/F) | 35/26 | 26/35 | 42/67 | 69/54 | 77/93 | 95/89 |
| Education (years) | 14.1 (4.1) | 15.0 (3.4) | 13.8 (3.8) | 14.5 (3.1) | 13.9 (3.9) | 14.7 (3.2) |
| MMSE | 24.2 (3.3) | 23.3 (2.0) | 24.0 (3.3) | 23.3 (2.0) | 24.1 (3.3) | 23.3 (2.0) |
| BPF (%) | 73.3 (4.2) | 65.9 (3.1) | 74.3 (4.8) | 66.1 (2.3) | 73.9 (4.6) | 66.0 (2.6) |
| BPF (%) range | 62.23‐80.83 | 59.84‐74.00 | 63.26‐86.37 | 60.35‐72.87 | 62.23‐86.37 | 59.84‐74.00 |
| IADL‐DAD (%) | 76.3 (21.6) | – | 75.6 (23.7) | – | 75.8 (22.9) | – |
| IADL‐DAD range | 30‐100 | – | 7‐100 | – | 7‐100 | – |
| FAQ | – | 14.0 (6.4) | – | 12.7 (7.1) | – | 13.1 (6.9) |
| FAQ range | – | 1‐30 | – | 0‐29 | – | 0‐30 |
Note. Means are represented with standard deviations in parentheses.
Abbreviations: ADNI, Alzheimer's Disease Neuroimaging Initiative; APOE, apolipoprotein E; BPF, brain parenchymal fraction; FAQ, Functional Activities Questionnaire.; IADL‐DAD, Instrumental Activities of Daily Living‐Disability Assessment Scale; MMSE, Mini‐Mental State Exam; n, sample size; SDS, Sunnybrook Dementia Study.