Table 2a.
Pregabalin effect on leg pain and disability.
| Reference(s) | Outcome | Comparison arm | N Pregabalin/N comparison | MD (CI 95%) |
|---|---|---|---|---|
| Kim 2016 Mathieson 2017 |
Leg pain at 2 weeks | Placebo | 166/158 | −0.19 (−0.67 to 0.29) |
| Kim 2016 Mathieson 2017 |
Leg pain at 8 weeks† | Placebo | 160/154 | −0.03 (−0.54 to 0.48) |
| Mathieson 2017 | Leg pain at 26 weeks | Placebo | 93/91 | −0.10 (−0.94 to 0.74) |
| Mathieson 2017 | Leg pain at 52 weeks | Placebo | 91/87 | 0.40 (−0.45 to 1.25) |
| Mathieson 2017 | Back pain at 2 weeks | Placebo | 101/95 | −0.30 (−1.07 to 0.47) |
| Mathieson 2017 | Back pain at 8 weeks | Placebo | 94/90 | 0.40 (−0.45 to 1.25) |
| Mathieson 2017 | Back pain at 26 weeks | Placebo | 87/88 | −0.30 (−1.22 to 0.62) |
| Mathieson 2017 | Back pain at 52 weeks | Placebo | 83/80 | 0.80 (−0.08 to 1.68) |
| Mathieson 2017 | Disability at 2 weeks | Placebo | 101/96 | −0.80 (−2.52 to 0.92) |
| Kim 2016 Mathieson 2017 |
Disability at 8 weeks† | Placebo | 153/150 | −0.08 (−0.30 to 0.15) |
| Mathieson 2017 | Disability at 26 weeks | Placebo | 85/87 | −1.40 (−3.63 to 0.83) |
| Mathieson 2017 | Disability at 52 weeks | Placebo | 83/79 | 0.80 (−1.48 to 3.08) |