Table 1.
Demographic information.
| Total sample (N = 214) |
Schizophrenia (N = 53) |
Healthy controls (N = 161) |
|||||
|---|---|---|---|---|---|---|---|
| Mean (S.D.a) | Relationship with plasma IL-6b (p value) | Statistic comparing schizophrenia and healthy controls (p value) | Mean (S.D. a) | Relationship with plasma IL-6b (p value) | Mean (S.D. a) | Relationship with plasma IL-6 b (p value) | |
| Age | 37.61 (12.163) | r = 0.112 (0.108) | t = 3.497 (0.001) | 42.55 (11.289) | r = 0.237 (0.101) | 35.98 (12.032) | r = -0.112 (0.161) |
| Gender (M:F) | 135:79 | t = 1.485 (0.139) | Chi-Square = 1.369 (0.242) | 37:16 | t = 0.900 (0.373) | 98:63 | t = 1.136 (0.258) |
| ART outliers | 6.7336 (13.81192) | r = 0.224 (0.001) | t = 1.851 (0.070) | 11.6226 (25.33258) | r = 0.220 (0.130) | 5.1242 (5.90525) | r = -0.011 (0.889) |
| Faces post-scan correct performance | 4.2523 (1.03546) | r = -0.140 (0.045) | t = 1.128 (0.260) | 4.1132 (1.13782) | r = -0.289 (0.044) | 4.2981 (0.99903) | r = 0.046 (0.568) |
| BMIc | 25.97 (4.702) | r = 0.179 (0.012) | t = 7.483 (<0.001) | 29.71 (4.795) | r = 0.138 (0.351) | 24.70 (3.942) | r = 0.032 (0.698) |
| Plasma IL-6b in pg/mld | 1.9964 (3.44161) | r = 1 | t = 2.122 (0.039) | 3.4596 (6.25757) | r = 1 | 1.5427 (1.64147) | r = 1 |
| Chlorpromazine equivalent score in mg/daye | – | – | – | 1023.22 (2194.449) | r = 0.005 (0.977) | – | – |
| PANSS positive total scoref | – | – | – | 8.75 (2.331) | r = 0.184 (0.216) | – | – |
| PANSS negative total scoref | – | – | – | 9.71 (3.823) | r = 0.297 (0.043) | – | – |
| PANSS general total scoref | – | – | – | 20.47 (4.076) | r = 0.291 (0.047) | – | – |
| PANSS totalf | – | – | – | 38.79 (8.185) | r = 0.329 (0.023) | – | – |
a
S.D. = standard deviation.
b
IL-6 = interleukin 6.
c
BMI = body mass index; BMI available for 52 of 53 participants in the schizophrenia group and 153 of 161 healthy controls.
d
Plasma IL-6 available for 49 of 53 participants in the schizophrenia group and 158 of 161 healthy controls.
e
Total chlorpromazine equivalent score available for 46 of 53 participants in the schizophrenia group.
f
PANSS = Positive and Negative Syndrome Scale Score; PANSS positive, negative and general scores available for 51 of 53 participants in the schizophrenia group; PANSS total score available for 52 of 53 participants in the schizophrenia group.