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. 2021 Sep 30;9:747743. doi: 10.3389/fped.2021.747743

Table 2.

Crude and standardized incidence rates.

Incidence rates (/100,000 person years) and 95% confidence intervals
Crude Standardized
WHO 2020 standard population European standard population U.S. standard population
TBI hospitalizations 687.1 689.2 (687.2–691.2) 688.0 (686.0–690.0) 681.7 (679.8–683.7)
TBI main diagnosis 626.8 629.7 (627.8–631.6) 628.4 (626.5–630.3) 622.5 (620.6–624.4)
Male 739.4
Female 631.7
Mechanical ventilation 4.8 4.7 (4.5–4.8) 4.7 (4.5–4.8) 4.6 (4.5–4.8)
Mortality 0.67 0.65 (0.59–0.71) 0.66 (0.60–0.72) 0.65 (0.59–0.71)
Resuscitation 0.39 0.39 (0.35–0.44) 0.39 (0.35–0.44) 0.39 (0.34–0.43)
Loss of consciousness 96.9 95.5 (94.7–96.2) 95.7 (94.9–96.4) 95.4 (94.6 – 96.1)
Intracranial injury 18.4 18.2 (17.9–18.6) 18.2 (17.9–18.6) 18.0 (17.7–18.4)
Subdural hemorrhage 6.5 6.4 (6.2–6.6) 6.4 (6.2–6.6) 6.3 (6.1–6.5)
Epidural hemorrhage 3.6 3.6 (3.5–3.8) 3.6 (3.5–3.8) 3.6 (3.5–3.7)
Subarachnoidal hemorrhage 3.2 3.1 (3.0–3.3) 3.2 (3.0–3.3) 3.1 (3.0–3.3)
Brain edema 1.9 1.8 (1.7–1.9) 1.8 (1.7–1.9) 1.8 (1.7–1.9)
Other intracranial injury 9.8 9.7 (9.4–9.9) 9.7 (9.4–9.9) 9.6 (9.4–9.8)
Neurosurgery 4.6 4.5 (4.3–4.6) 4.5 (4.3–4.6) 4.4 (4.3–4.6)
EVD 1.6 1.6 (1.5–1.6) 1.6 (1.5–1.7) 1.5 (1.5–1.6)
Evacuation of hematoma 2.0 1.9 (1.8–2.1) 1.9 (1.8–2.1) 1.9 (1.8–2.0)
DC 0.94 0.92 (0.85–0.99) 0.92 (0.85–0.99) 0.91 (0.84–0.99)
Visceral surgery 1.6 1.5 (1.4–1.6) 1.5 (1.4–1.6) 1.5 (1.4–1.6)
Imaging 71.5 69.2 (68.6–69.9) 69.7 (69.1–70.3) 69.5 (68.8–70.1)
CT only 42.5 40.7 (40.2–41.2) 41.1 (40.6–41.6) 40.8 (40.3–41.3)
MRI only 22.3 21.9 (21.6–22.3) 22.0 (21.6- 22.3) 22.1 (21.7–22.4)
CT and MRI 6.7 6.6 (6.4–6.8) 6.6 (6.4–6.8) 6.6 (6.4–6.8)
Seizures* 5.3 5.3 (5.1–5.4) 5.3 (5.1–5.4) 5.3 (5.1–5.4)
Epileptic state 0.33 0.33 (0.29–0.38) 0.33 (0.29–0.38) 0.32 (0.28–0.37)

TBI, traumatic brain injury; SD, standard deviation; CT, computed tomography; MRI, magnetic resonance imaging; EVD, external cerebrospinal fluid drainage and/or invasive ICP monitoring; DC, decompressive craniectomy;

*

including any epilepsy.