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. 2021 Sep 28;22(6):1372. doi: 10.3892/etm.2021.10806

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Copyright: © Jin et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Overexpression of DVL3 reverses the sh-PTK7-induced inhibition of SCC-9 cell migration and invasion. (A) Wound healing and (B) Transwell assays were performed to analyze cell migration and invasion, respectively (magnification, x100; scale bar, 100 mm). (C) MMP2 and MMP9 expression in SCC-9 cells following transfection with sh-PTK7, pcDNA or pcDNA-DVL3 were analyzed using western blotting. ^***P<0.001 vs. control; ^##P<0.01 and ^###P<0.001 vs. sh-PTK7 + pcDNA. DVL3, dishevelled segment polarity protein; sh, short hairpin RNA; PTK7, protein tyrosine kinase 7.