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Characteristics of pierced capsule holes of each capsule.
| Hole diameter, mm | Hole area, mm2 | |
|---|---|---|
| G-Cap | 1.28±0.02 | 1.56±0.08 |
| PEG/G-Cap | 1.14±0.98 | 1.26±0.06 |
| HPMC-Cap | 1.17±0.15 | 1.35±0.19 |
Each value represents the mean ± standard error of measurements. n=10. G-Cap, gelatin capsule; PEG/G-Cap, gelatin capsule containing 5% PEG4000 as plasticizer; HPMC-Cap, hydroxypropyl methylcellulose capsule.
