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mRNA expression levels of CMPK2, NLRP3 and inflammatory factors in H/R model of RAW 264.7 cells. (A) The mRNA levels of CMPK2 were measured at different time points after reoxygenation. The mRNA expression levels of (B) NLRP3, (C) TNF-α, (D) IL-1β and (E) IL-18 were detected following H/R treatment. *P<0.05, **P<0.01 vs. control groups. CMPK2, cytidine monophosphate kinase 2; NLRP3, NLR family pyrin domain containing 3; H/R, hypoxia/reoxygenation.
