Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 24;22(6):1358. doi: 10.3892/etm.2021.10793

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Luo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Suppression of CMPK2 alleviates I/R-induced deterioration of hepatic injury. (A) Protein detection of CMPK2 in liver tissue. Secretion of (B) IL-18 and (C) IL-1β was measured by ELISA. Hepatocellular function of experimental mice was evaluated by detecting the release of (D) AST and (E) ALT. (F and G) Histological changes of the liver in the sham, I/R, I/R + scramble siRNA and I/R + CMPK2 siRNA groups. Original magnification, x200. ^**P<0.01, ^***P<0.001 vs. sham group; ^#P<0.05, ^##P<0.01 vs. I/R group. CMPK2, cytidine monophosphate kinase 2; NLRP3, NLR family pyrin domain containing 3; I/R, ischemia/reperfusion; siRNA, small interfering RNA; ALT, alanine aminotransferase; AST, aspartate aminotransferase.