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Analysis of clinical parameters. (A) Mean tear volume, (B) tear film break-up time, (C) corneal fluorescein staining scores and (D) representative images of corneal fluorescein staining in UT, EDE, 0.05% CsA emulsion-treated and 0.1% CsA CE-treated mice of the severe dry eye and non-severe dry eye groups at 0 and 10 days. *P<0.05 vs. EDE΄ †P<0.05 vs. 0.05% CsA. UT, untreated control; EDE, experimental dry eye; CsA, cyclosporin A; CE, cationic emulsion.
