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. 2021 Oct 12;153(12):e202112969. doi: 10.1085/jgp.202112969

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© 2021 Eldstrom et al.

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Figure 3. — ML277 increases the amplitude of EQQ and EQ openings. (A) Single-channel recordings of EQQ (top) and EQ (bottom) before (blue traces) and after addition of 1 µM ML277 (red traces) from the same patch as control data. The voltage protocol is shown above the data. (B) All-points amplitude histograms of three active sweeps of EQQ before (blue) and after 1 µM ML277 addition (red; top) and 27 active sweeps combined from three different cells of EQ before (blue) and after 1 µM ML277 addition (bottom). (C) Scatter plot of first latencies to opening of the active sweeps for EQ, EQQ, and EQQQQ before and after ML277 exposure. See Table 3 for mean values.