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. 2021 Oct 13;14:133. doi: 10.1186/s13048-021-00854-5

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Ovarian tissue structure (a, c, and e: 50 × ; b, d, and f: 200 ×). a and b Preantral follicles (black dotted arrows) and antral follicles (thick black arrows) were visible in the young control group. c and d In the model control group, the nuclei were condensed (thick black arrow). In addition, a small number of infiltrating inflammatory cells (thin black arrow) and a small amount of brownish-yellow pigment deposition (black dotted arrow) were observed. e and f In the mUCMSC treatment group, more atretic follicles were observed, and the structures of the inferior antral follicles (thick black arrows) and atretic follicles (thin black arrows) were significantly improved. g Observation of ovaries from each group. h Numbers of follicles at various stages in each group; * P < 0.05 compared with the model group