Fig. 2.

Hammersmith Functional Motor Scale Expanded results reporting author, HFMSE results (0–66 scale, mean ± SD), sample size, mean age (years, range/SD), mean baseline HFMSE (range/SD). a Adult population, b pediatric population. Key to figure: dashed line = 95% Confidence interval, plain line = Standard Deviation, square = SMA 2, circle = SMA 3, diamond = ambulant SMA 3, triangle = non ambulant SMA 3, square + circle + triangle = mix phenotypes. Bold font = Median value, Italic = Mean value. Color coding: light blue =  ~10 months from initiation of drug, Red =  ~12 months from initiation of drug, Green =  ~24 months from infusion. Grey shade = SMA 2, White shade = SMA 3, Striped shade = mixed phenotypes. *Mean/median values of the baseline population non excluding drop-outs at T10, 14 or 24 months of follow-up, **mean/median values of the baseline population of both SMA II and III combined