Table 3.
Laboratory characteristics of the GAUCHERITE cohort and subgroups at recruitment
| Variables | Categories* | Entire cohort (N = 250) | Children (N = 26) |
Adults (N = 224) |
Gaucher Type 1 (N = 223) | Gaucher Type 3 (N = 27) |
|---|---|---|---|---|---|---|
| Haemoglobin | Number | 211 | 11 | 200 | 193 | 18 |
| g/L, mean ± SD | 139.5 ± 13.9 | 133.7 ± 11.6 | 139.9 ± 14.0 | 140.3 ± 13.6 | 131.3 ± 15.2 | |
| Median (range) | 139 (101–178) | 131 (118–151) | 139 (101–178) | 139 (101–178) | 131 (103–160) | |
| With spleen | Number | 157 | 11 | 146 | 146 | 11 |
| g/L, mean ± SD | 140 ± 15 | 134 ± 12 | 141 ± 15 | 141 ± 14 | 129 ± 17 | |
| Median (range) | 139 (101–178) | 131 (118–151) | 140 (101–178) | 140 (101–178) | 131 (103–160) | |
| Without spleen | Number | 54 | – | 54 | 47 | 7 |
| g/L, mean ± SD | 137 ± 11 | – | 137 ± 11 | 138 ± 11 | 135 ± 14 | |
| Median (range) | 138 (116–163) | – | 138 (116–163) | 138 (116–163) | 131 (120–153) | |
| Platelet count | Number | 208 | 11 | 197 | 190 | 18 |
| 109/L, mean ± SD | 200 ± 74 | 229 ± 62 | 198 ± 74 | 196 ± 74 | 244 ± 52 | |
| Median (range) | 189 (39–489) | 213 (151–337) | 187 (39–489) | 184 (39–489) | 234 (147–337) | |
| With spleen | Number | 155 | 11 | 144 | 144 | 11 |
| 109/L, mean ± SD | 178 ± 56 | 229 ± 62 | 174 ± 54 | 173 ± 53 | 242 ± 58 | |
| Median (range) | 175 (39–337) | 213 (151–337) | 175 (39–321) | 175 (39–321) | 230 (147–337) | |
| Without spleen | Number | 53 | – | 53 | 46 | 7 |
| 109/L, mean ± SD | 263 ± 82 | – | 263 ± 82 | 265 ± 87 | 248 ± 46 | |
| Median (range) | 253 (87–489) | – | 253 (87–489) | 253.5 (87–489) | 236 (197–318) |
SD standard deviation
*Continuous variables are expressed as mean ± SD and median (range).