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. 2000 Jan;20(2):648–655. doi: 10.1128/mcb.20.2.648-655.2000

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Copyright © 2000, American Society for Microbiology

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FIG. 4 — FISH analysis of long-range Cre recombination products on Chr 11. (A) Del(11)5Brd-Dp(11)5Brd, a 22-cM deletion chromosome and a 22-cM duplication chromosome produced by a trans event between Hsd17b1 and D11Mit69. (B) Del(11)5Brd-WT-WT, a 22-cM deletion chromosome produced by a cis event between Hsd17b1 and D11Mit69, while the remaining wild-type chromosome is duplicated to survive. (C) The same as in panel B except that the duplicated wild-type chromosomes are in a Robertsonian (or iso-chromosome) configuration. (D) Del(11)7Brd-Dp(11)7Brd, a 60-cM deletion chromosome and a 60-cM duplication chromosome produced by a trans event between Hsd17b1 and D11Mit71. Colors: yellow, BAC 232M23 (D11Mit320); red, BAC 330H2 (D11Mit263); green, BAC 330P14 (D11Mit11). Two or more probes were differentially labeled and artificially colored.