FIGURE 2.

Characterization of (DOX+ACE)@ZIF‐8. A, Particle size distribution of (DOX+ACE)@ZIF‐8 measured by dynamic light scattering. B and C, Representative SEM images of ZIF‐8 and (DOX+ACE)@ZIF‐8; scale bars, 200 nm. D, Elemental distribution of ZIF‐8 and (DOX+ACE)@ZIF‐8 mapped by energy‐dispersive X‐ray spectroscopy. E, XRD spectra of ZIF‐8 and (DOX+ACE). F, TGA analysis of ZIF‐8 and (DOX+ACE). G, UV‐Vis DRS spectra of DOX, ACE, Zn(NO₃)₂, 2‐MI, and H₂O. H, The standard curve of DOX at 480 nm and ACE at 262 nm. I, pH‐responsive release of DOX and ACE from (DOX+ACE)@ZIF‐8 in PBS (pH 5.0, 6.8, and 7.4) at 37°C